nedocromil sodium

Last edited 11/2021 and last reviewed 01/2022

Nedocromil sodium is indicated for the prophylaxis of asthma.

It may be used in conjunction with inhaled beta-2 agonists and corticosteroids to allow the reduction in the dose of either or both drugs.

Withdrawal of sodium cromoglicate inhaler in the UK (1):

  • the asthma preventer inhaler Intal (sodium cromoglicate) is being discontinued, with stock expected to be exhausted by the end of January 2022
  • the BTS/SIGN asthma guideline considers inhaled corticosteroids to be the first-choice preventer drug, and sodium cromoglicate as an alternative but less effective preventer therapy
  • the Global Initiative for Asthma (GINA) does not recommend the use of chromones in children age 6-11 years because of low efficacy, and does not include this class of agent as a treatment option in adults

Reference:

  • NHS. Medicine Supply Notification (8/11/2021) - Sodium cromoglicate (Intal (R)) CFC-free 5mg inhaler