clinical features
Last reviewed 01/2018
Most infections in humans are asymptomatic. However, when present there are a wide range of symptoms:
- mild, self-limiting, non-specific infectious mononucleosis syndrome
- disseminated, fulminating disease that may damage the brain, eyes, muscles, liver, and lungs
- in association with AIDS there is often a focal neurological defect with raised intracranial pressure secondary to a space-occupying lesion
- severe manifestations are seen principally in the immunocompromised patients - for example in AIDS - and in fetuses infected transplacentally as a result of maternal infection
- chorioretinitis may be associated with all forms, but it is usually a late sequel of congenital disease