classification
Last reviewed 03/2022
A pathological classification of porphyrias concentrates on the site of the defect in haem synthesis:
- defects in the liver cause hepatic porphyrias
- defects in the marrow cause erythropoietic porphyrias
A clinically more useful classification is the division in to acute and non-acute porphyrias:
- acute poryphrias typically present with abdominal pain and neuropsychiatric crises
- non-acute porphyrias cause photosensitivity