skin sclerosis (possible causes)
Last reviewed 11/2020
Differential diagnosis of skin sclerosis
- localised scleroderma
- systemic sclerosis
- Infiltrative disorders
- amyloidosis
- scleromyxoedema
- scleroderma of Buschke
- nephrogenic systemic fibrosis
- Inflammatory disorders
- overlap connective tissue diseases (mixed connective tissue disease)
- eosinophilic fasciitis
- chronic graft versus host disease
- lichen sclerosus et atrophicus
- sarcoidosis
- carcinoid syndrome
- silicosis
- Metabolic disorders
- myxoedema
- porphyria cutanea tarda
- congenital porphyrias
- acromegaly
- chemically induced eg bleomycin, vinyl chloride, pentazocine
- toxic oil syndrome
- repetitive manual work (skin on hands)
Reference:
- 1) Arthritis Research Campaign (2010). Topical Reviews - Systemic sclerosis and related disorders.