refractory status epilepticus (RSE)
Last reviewed 01/2018
refractory status epilepticus (RSE)
Refractory status epilepticus (RSE) is when a patient is not responding to standard treatment regimens for status epilepticus.
The definition of RSE is not clear and there exist some controversies regarding this:
- the number of AEDs to which the patient did not respond. Majority of experts consider RSE after failure of adequately dosed initial benzodiazepine and one AED.
- duration of SE after initiation of treatment. Most experts no longer consider duration to be a criterion for classification of RSE.
Reference: