lymphadenopathy and hypogammaglobulinaemia
Last reviewed 01/2018
This condition usually occurs in adolescence, comprising:
- febrile illness
- lymphadenopathy
- idiopathic thrombocytopenic purpura
There is usually spontaneous recovery over a period of a few weeks. However after a period of about 2-3 months the patient may present with recurrent infections, splenomegaly, lymphopaenia and hypogammaglobulinaemia.
Often there is gross generalised lymphadenopathy which on histological examination reveals germinal centre hyperplasia.