pigmented lesions in the mouth

Last reviewed 01/2018

Causes include:

  • heavy metals - lead, bismuth, iron - a dark line below the gingival lining
  • drugs
    • oral contraceptive pill - black or brown areas anywhere in the mouth
    • antimalarials
  • Addison's disease - bluish tinge opposite the molars
  • Peutz-Jegher spots - brown spots on the lips
  • telangiectasia - may suggest Osler-Weber-Rendu syndrome
  • melanoma

Tiny yellow spots in the mouth may be Fordyce spots - sebaceous glands.