Ann Arbor staging criteria
Last reviewed 11/2023
Stage I
- involvement of one lymph node or one extranodal organ or site (IE)
Stage II
- involvement of two or more lymph node regions on the same side of the diaphragm, or localised involvement of an extranodal site or organ (IIE) and one or more lymph node regions on the same side of the diaphragm
Stage III
- involvement of lymph node regions on both sides of the diaphragm, which might be accompanied by localised involvement of an extranodal organ or site (IIIE) or spleen (IIIS) or both (IIISE); the spleen is regarded as nodal
Stage IV
- diff use or disseminated involvement of one or more distant extranodal organs with or without associated lymph node involvement
Modifiers
A - absence of B symptoms
B - temperature >38°C, night sweats, and weight loss of greater than 10% of bodyweight in the
6 months preceding admission are defined as systemic symptoms
Localised extralymphatic lesions with or without associated lymph node involvement are termed 'E' (extranodal) lesions.
Reference:
staging and prognosis of Hodgkin's lymphoma based on Ann Arbor staging criteria