clinical pharmacokinetics
Last reviewed 01/2023
Points of note about the pharmacokinetics of Gabapentin:
- it does not induce liver enzymes
- it does not bind to plasma proteins
- half-life is 5-7 hours
- dose should be adjusted on the basis of clinical symptoms and signs as well as seizure response
- it does not interact with other antiepileptic drugs or reduce the efficacy of oral contraceptives