clinical features

Last reviewed 01/2018

Presentation is associated with the exocrine pancreatic insufficiency.

Other clinical features include

  • chronic or cyclical failure of haematopoeisis resulting in:
    • neutropaenia
    • pancytopaenia
    • isolated thrombocytopaenia
  • skeletal abnormalities
  • recurrent infections
  • growth retardation
  • abnormal liver function
  • dental abnormalities
  • developmental delay