glycogen (glycolysis)
Last reviewed 01/2018
Glycogen can liberate glucose for entry into glycolysis. Hepatocytes are capable of this pathway but instead tend to liberate glucose to the blood when cellular reserves are low; this pathway and its regulation are considered further in the submenu on glycogenolysis.
In other cells, the following reactions occur:
- glycogen phosphorylase cleaves glycogen of 1 glucose molecule that is phosphorylated to produce glucose-1-phosphate
- phosphoglucomutase converts glucose-1-phosphate into glucose-6-phosphate
- glucose-6-phosphate is able to enter the glycolytic pathway