type 1 hyperlipidaemia
Last reviewed 01/2018
Type I hyperlipidaemia is hyperchylomicronaemia:
- normal serum cholesterol
- increased triglyceride primarily in chylomicrons
- apo-CII deficiency or lipoprotein lipase deficiency
- risk of atherosclerosis is thought to be slight
- features include:
- recessive inheritance
- eruptive xanthomata
- lipaemia retinalis
- acute pancreatitis
Note that this classification as a type I hyperlipidaemia is a biochemical one and that a child with type I hyperlipidaemia (hyperchylomicronaemia) may develop a type V hyperlipidaemia (hyperchylomicronaemia and increased VLDL) as an adult.
diagnosis and mechanism of Types I and V hyperlipidaemia