rheumatoid factor positive disease
Last reviewed 01/2023
This is a vast list that includes:
Joint diseases:
- Sjogren's syndrome (90%)
- rheumatoid arthritis (80%)
- SLE (50%)
- polymyositis/dermatomyositis (50%)
- scleroderma/systemic sclerosis (30%)
- mixed connective tissue disease
- chronic juvenile arthritis
Chronic infections (low titres):
- subacute bacterial endocarditis
- leprosy
- malaria
- tuberculosis
- syphilis
- kala-azar
Miscellaneous
- autoimmune chronic active hepatitis
- fibrosing alveolitis
- sarcoidosis
- paraproteinaemia e.g. multiple myeloma, Waldenstrom's macroglobulinaemia
- in elderly patients or in relatives of patients with rheumatoid arthritis
systemic lupus erythematosus (SLE)
infective endocarditis (subacute)