interactions
Last reviewed 01/2018
Various drugs affect the half-life of theophylline:
- increased half-life is seen in heart failure, cirrhosis, viral infections, and drugs e.g. erythromycin, ciprofloxacin, cimetidine
- decreased half-life is seen in heavy drinkers, smokers, and by drugs e.g. barbiturates, phenytoin, carbamazepine, rifampicin