vehicle used with topical steroid

Last reviewed 01/2018

The choice of vehicle can affect the use and penetration of the medication resulting in varying in potency of a particular topical steroid (1). Numerous types of vehicle formulations are available and the selection depends on the type of lesion and the area of the body affected (2).

  • ointments
    • petrolatum based and provides more lubrication and occlusion (increases absorption) when compared to other preparations (3)
    • useful in treating dry or thick, hyperkeratotic lesions and for areas with thick skin (like in palms and soles) (2)
    • should not be applied to hairy areas and if used on intertriginous areas may result in maceration and folliculitis (3)
  • creams
    • generally less potent than ointments, it has good lubricating qualities and are cosmetically more acceptable to patients
    • useful in treatment of moist and weeping areas of the skin (4)
    • may cause irritation, stinging, and allergic reaction to preservatives it contains (3)
  • gels
    • non-greasy and non-occlusive and used for hairy or facial areas (3)
    • useful for exudative inflammation e.g. – poison ivy (4)
  • lotions
    • contain alcohol and used in hairy areas, leaves very little residue (3)
    • useful in conditions with acute inflammation or tenderness e.g. - acute contact dermatitis (4)
  • foams, mousses, and shampoos
    • effective when used on the scalp
    • spreads easily resulting in increased permeability with little or no residue (4)

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